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1. 发明授权

US07390464B2 Fluidic circuits for sample preparation including bio-discs and methods relating thereto 失效
标题翻译：用于样品制备的流体回路，包括生物盘和与其相关的方法
公开(公告)号：US07390464B2
公开(公告)日：2008-06-24
申请号：US10899388
申请日：2004-07-26
申请人： Horacio Kido , James R. Norton , James H. Coombs
发明人： Horacio Kido , James R. Norton , James H. Coombs
IPC分类号： B01L3/00
CPC分类号： B01L3/502753 , B01L3/5025 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L2200/0621 , B01L2200/10 , B01L2300/0806 , B01L2400/0406 , B01L2400/0409 , B01L2400/0688 , B01L2400/0694 , Y10T436/111666
摘要： A fluidic circuit for receiving a fluid and separating a component of a fluid from the fluid comprises a separation chamber for receiving the fluid, an air chamber in fluid communication with the separation chamber, and a return channel in fluid communication with the separation chamber. In an advantageous embodiment, the fluidic circuit is subjected to a force, such as a centrifugal force, so that substantially all of the component of the fluid is moved to the return channel while substantially all remaining portions of the fluid are moved to the separation chamber.
摘要翻译：用于接收流体并从流体分离流体的分量的流体回路包括用于接收流体的分离室，与分离室流体连通的空气室和与分离室流体连通的返回通道。在有利的实施例中，流体回路受到诸如离心力的力，使得流体的基本上所有部件移动到返回通道，同时基本上所有剩余部分的流体被移动到分离室。

2. 发明授权

US5876822A Reversible optical information medium 失效
标题翻译：可逆光信息媒体
公开(公告)号：US5876822A
公开(公告)日：1999-03-02
申请号：US795819
申请日：1997-02-06
申请人： Guofu F. Zhou , James H. Coombs , Johan P. W. B. Duchateau
发明人： Guofu F. Zhou , James H. Coombs , Johan P. W. B. Duchateau
IPC分类号： G11B7/24 , G11B7/243 , G11B7/2531 , G11B7/2533 , G11B7/2534 , G11B7/258 , G11B7/2585 , G11B7/2595 , B32B3/00
CPC分类号： G11B7/258 , G11B7/24 , G11B7/243 , G11B2007/24312 , G11B2007/24314 , G11B2007/24316 , G11B7/2531 , G11B7/2533 , G11B7/2534 , G11B7/2585 , G11B7/2595 , Y10S428/913 , Y10S430/146 , Y10T428/21
摘要： A description is given of an reversible optical information medium comprising a substrate (1), a first dielectric layer (2), a phase-change recording layer on the basis of Ge-Sb-Te (3), a second dielectric layer (4), and a metal mirror layer (5). The recording layer (3) comprises an alloy having the composition Ge.sub.50x Sb.sub.40-40x Te.sub.60-10x, in atom %, wherein0.166.ltoreq.x.ltoreq.0.444and wherein the layer thickness d.sub.3 of said recording layer (3) ranges between 25 and 35 nm. Such a medium is suitable for high speed recording (i.e. at least twice the CD-speed), and has a large cyclability of at least 10.sup.5 direct overwrite cycles.
摘要翻译：给出了包括基板（1），第一介电层（2），基于Ge-Sb-Te（3）的相变记录层，第二介电层（4））和金属镜层（5）。记录层（3）包括原子％组成为Ge50xSb40-40xTe60-10x的合金，其中0.166≤x≤0.444，并且其中所述记录层（3）的层厚度d3在25和35之间 nm。这种介质适用于高速记录（即至少是CD速度的两倍），并且具有至少105个直接重写周期的大的循环性。

3. 发明授权

US5479392A Phase change record carries having crystalline nuclei and/or which produce crystallization structures when information is written thereon enabling that information to be more easily erased 失效
标题翻译：相变记录具有结晶核和/或当其上写入信息时产生结晶结构，使得能够更容易地擦除信息
公开(公告)号：US5479392A
公开(公告)日：1995-12-26
申请号：US285834
申请日：1994-08-04
申请人： Antonius H. M. Holtslag , James H. Coombs , Wilma Van Es-Spiekman
发明人： Antonius H. M. Holtslag , James H. Coombs , Wilma Van Es-Spiekman
IPC分类号： G11B7/00 , G11B7/0045 , G11B7/0055 , G11B7/006 , G11B7/125 , G11B7/30
CPC分类号： G11B7/126 , G11B7/00557 , G11B7/006
摘要： Information storage system, device and record carriers for improved erasing of information written on a record carrier. A radiation beam is focused on a recording layer of a record carrier containing phase-change material. Crystalline information areas are written on initially amorphous portions of the recording layer by means of the radiation beam having its intensity modulated in accordance with write pulses. The information areas are erased (and changed back into amorphous portions) by means of the radiation beam having its intensity modulated in accordance with erase pulses. The time duration of each of the erase pulses (and, therefore, the intensity of the radiation beam being modulated in accordance therewith to heat the recording layer) and the cooling time of the recording layer thereafter is short enough that areas of the recording layer which are heated during erasing to a temperature above the crystallization temperature of the recording layer but lower than the melting point of the recording layer remain above the crystallization temperature for a period of time which is shorter than the crystallization time for the recording layer. The recording layer may contain a track and have more crystallization nuclei proximate to a centerline of the track than away from the centerline. In addition, the record carrier may be such that its reflection is larger when the recording layer has an amorphous structure than when it has a crystalline structure.
摘要翻译：信息存储系统，设备和记录载体，用于改善擦写记录载体上的信息。辐射束聚焦在包含相变材料的记录载体的记录层上。结晶信息区域通过具有根据写入脉冲调制的强度的辐射束写在记录层的初始非晶体部分上。信息区域通过具有根据擦除脉冲调制的强度的辐射束被擦除（并且变回非晶部分）。擦除脉冲的持续时间（并且因此，根据其加热记录层的辐射束的强度）和其后的记录层的冷却时间足够短，使得记录层的区域在擦除到高于记录层的结晶温度但低于记录层的熔点的温度的温度下被加热保持高于结晶温度超过记录层的结晶时间的时间段。记录层可以包含轨道并且具有比远离中心线更靠近轨道的中心线的更多的结晶核。此外，记录载体可以是当记录层具有非晶体结构时比其具有晶体结构时的反射更大。

4. 发明授权

US06256285B1 Optical scanning device 失效
标题翻译：光学扫描装置
公开(公告)号：US06256285B1
公开(公告)日：2001-07-03
申请号：US09184532
申请日：1998-11-02
申请人： James H. Coombs
发明人： James H. Coombs
IPC分类号： G11B700
CPC分类号： G11B7/131 , G11B7/0901 , G11B7/0908 , G11B7/0912 , G11B7/1353 , G11B2007/0013
摘要： An optical scanning device is described which can scan a record carrier by a radiation beam. A dividing element directs radiation reflected from the record carrier to a detection system. The detection system includes at least three detectors. The dividing element has at least three gratings, each forming a sub-beam directed to one of the detectors. The longest dimension of each detector is substantially perpendicular to the bisector of the appertaining sector.
摘要翻译：描述了可以通过辐射束扫描记录载体的光学扫描装置。分离元件将从记录载体反射的辐射引导到检测系统。检测系统包括至少三个检测器。分隔元件具有至少三个光栅，每个光栅形成指向一个检测器的子光束。每个检测器的最长尺寸基本上垂直于相应扇区的平分线。

5. 发明授权

US5708638A Device for optically scanning a recording medium by focusing the best focus or the paraxial focus to the information layer 失效
标题翻译：用于通过将最佳聚焦或近轴聚焦聚焦到信息层来光学扫描记录介质的装置
公开(公告)号：US5708638A
公开(公告)日：1998-01-13
申请号：US615931
申请日：1996-03-14
申请人： Josephus J. M. Braat , Igolt P. D. Ubbens , James H. Coombs , Jacob Sonneveld , Jacobus P. C. Kroon , Petrus T. Jutte
发明人： Josephus J. M. Braat , Igolt P. D. Ubbens , James H. Coombs , Jacob Sonneveld , Jacobus P. C. Kroon , Petrus T. Jutte
IPC分类号： H04N5/783 , G11B5/008 , G11B5/027 , G11B7/00 , G11B7/0037 , G11B7/085 , G11B7/09 , G11B7/131 , G11B7/133 , G11B7/1353 , G11B7/1372 , G11B7/1381 , G11B15/02 , G11B15/12 , G11B15/14 , G11B15/18 , G11B15/473 , G11B19/12 , G11B20/02 , G11B27/032 , G11B27/036 , G11B27/36 , G11B33/10
CPC分类号： G11B7/131 , G11B15/02 , G11B15/125 , G11B15/1875 , G11B19/12 , G11B27/036 , G11B27/36 , G11B7/0037 , G11B7/0908 , G11B7/0909 , G11B7/133 , G11B7/1353 , G11B7/1372 , G11B7/1381 , G11B15/4731 , G11B2007/0006 , G11B2007/0013 , G11B2220/90 , G11B27/032 , G11B33/10 , G11B5/0086 , G11B7/0916
摘要： An optical scanning device can scan two types of record carriers each having a transparent layer with a different thickness, in which a radiation beam scans an information layer of the record carrier through the transparent layer. When scanning a first type of record carrier the best focus of a scanning radiation beam is positioned on the information layer and when scanning a second type of record carrier the paraxial focus of the radiation beam is positioned on the information layer.
摘要翻译：光学扫描装置可以扫描具有不同厚度的透明层的两种类型的记录载体，其中辐射束通过透明层扫描记录载体的信息层。当扫描第一类型的记录载体时，扫描辐射束的最佳焦点位于信息层上，并且当扫描第二类型的记录载体时，辐射束的近轴焦点位于信息层上。

6. 发明授权

US5255263A Information reading system and record carrier and reading device for use in such a system 失效
标题翻译：信息读取系统和记录载体和读取装置，用于这种系统
公开(公告)号：US5255263A
公开(公告)日：1993-10-19
申请号：US845289
申请日：1992-03-03
申请人： Cornelis M. J. Van Uijen , Yvonne A. Boersma , James H. Coombs
发明人： Cornelis M. J. Van Uijen , Yvonne A. Boersma , James H. Coombs
IPC分类号： G11B7/00 , G11B7/005 , G11B7/007 , G11B7/013 , G11B7/09 , G11B7/095 , G11B7/14 , G11B11/105 , G11B21/00 , G11B5/84
CPC分类号： G11B7/24085 , G11B11/10515 , G11B7/005 , G11B7/14 , G11B7/24088
摘要： The disclosed information reading system comprises a record carrier (1) having at least two parallel tracks (2a, 2b) whose mutual distance is so small that the radiation beam (10) is modulated by the information patterns of the two tracks (2a, 2b) when the tracks are scanned by a focused radiation beam (10) along a line (18) indicating the center between the tracks (2a, 2b). The tracks comprise elementary areas, with the positions of the boundaries (80) of the elementary areas of the two tracks, viewed in the track direction, corresponding to each other. The information patterns in the tracks comprise elementary areas occupied by a mark and unoccupied elementary areas. The occupied elementary areas have a different influence on the radiation than the unoccupied elementary areas. When the two tracks (2a, 2b) are scanned, the center (17) of the scanning spot (14) is directed onto a line (18) which is located centrally between the tracks (2a, 2b). A radiation beam modulated by the scanned information pattern is projected onto a detection system (12). The information (I1, I2, I) which has been read is at least partly derived on the basis of one or more detection signals (Vt, Vppr, Vppt, Vppd) which are supplied by the detection system (12) at the instants when the radiation beam passes the boundaries (80) of the elementary areas.

7. 发明申请

US20080317634A1 FLUIDIC CIRCUITS FOR SAMPLE PREPARATION INCLUDING BIO-DISCS AND METHODS RELATING THERETO 审中-公开
标题翻译：用于样品制备的流体电路，包括生物芯片和与之相关的方法
公开(公告)号：US20080317634A1
公开(公告)日：2008-12-25
申请号：US12144405
申请日：2008-06-23
申请人： Horacio Kido , James R. Norton , James H. Coombs
发明人： Horacio Kido , James R. Norton , James H. Coombs
IPC分类号： B04B5/00
CPC分类号： B01L3/502753 , B01L3/5025 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L2200/0621 , B01L2200/10 , B01L2300/0806 , B01L2400/0406 , B01L2400/0409 , B01L2400/0688 , B01L2400/0694 , Y10T436/111666
摘要： A fluidic circuit for receiving a fluid and separating a component of a fluid from the fluid comprises a separation chamber for receiving the fluid, an air chamber in fluid communication with the separation chamber, and a return channel in fluid communication with the separation chamber. In an advantageous embodiment, the fluidic circuit is subjected to a force, such as a centrifugal force, so that substantially all of the component of the fluid is moved to the return channel while substantially all remaining portions of the fluid are moved to the separation chamber.
摘要翻译：用于接收流体并从流体分离流体的分量的流体回路包括用于接收流体的分离室，与分离室流体连通的空气室和与分离室流体连通的返回通道。在有利的实施例中，流体回路受到诸如离心力的力，使得流体的基本上所有部件移动到返回通道，同时基本上所有剩余部分的流体被移动到分离室。

8. 发明授权

US5935672A Reversible optical information medium 失效
标题翻译：可逆光信息媒体
公开(公告)号：US5935672A
公开(公告)日：1999-08-10
申请号：US891340
申请日：1997-07-10
申请人： Guo-Fu Zhou , James H. Coombs , Johan P. W. B. Duchateau
发明人： Guo-Fu Zhou , James H. Coombs , Johan P. W. B. Duchateau
IPC分类号： G11B7/24 , G11B7/243 , G11B7/2531 , G11B7/2534 , G11B7/258 , G11B7/2585 , G11B7/2595 , B32B3/02
CPC分类号： G11B7/258 , G11B7/24 , G11B7/243 , G11B2007/24312 , G11B2007/24314 , G11B2007/24316 , G11B7/2531 , G11B7/2534 , G11B7/2585 , G11B7/2595 , Y10S428/913 , Y10S430/146 , Y10T428/21 , Y10T428/31678
摘要： A description is given of an reversible optical information medium comprising a substrate, a first dielectric layer, a phase-change recording layer on the basis of Ge--Sb--Te, a second dielectric layer, and a metal mirror layer. The recording layer comprises an alloy having the composition Ge.sub.50x Sb.sub.40-40x Te.sub.60-10x in atom %, wherein0.166.ltoreq.x.ltoreq.0.444and wherein the layer thickness d.sub.3 of said recording layer ranges between 25 and 35 nm. Such a medium is suitable for high speed recording (i.e. at least twice the CD-speed), and has a large cyclability of at least 10.sup.5 direct overwrite cycles.
摘要翻译：给出了包括基板，第一介电层，基于Ge-Sb-Te的相变记录层，第二介电层和金属镜面层的可逆光学信息介质的描述。记录层包括原子％为Ge50xSb40-40xTe60-10x组成的合金，其中，0.66×（x≤0.444），其中所述记录层的层厚度d3在25和35nm之间。这种介质适用于高速记录（即至少是CD速度的两倍），并且具有至少105个直接重写周期的大的循环性。

9. 发明授权

US5802032A Method and device for recording a mark having a substantially constant number of pulses per unit length independent of writing speed on an optical information carrier 失效
标题翻译：用于在光学信息载体上独立于写入速度记录每单位长度具有基本上恒定数目的脉冲的标记的方法和装置
公开(公告)号：US5802032A
公开(公告)日：1998-09-01
申请号：US800443
申请日：1997-02-18
申请人： Bernardus A.J. Jacobs , James H. Coombs , Johannes H.M. Spruit , Johan P.W.B. Duchateau , Guofu F. Zhou
发明人： Bernardus A.J. Jacobs , James H. Coombs , Johannes H.M. Spruit , Johan P.W.B. Duchateau , Guofu F. Zhou
IPC分类号： G11B7/00 , G11B7/0045 , G11B7/0055 , G11B7/006 , G11B7/125 , G11B20/08 , G11B20/12 , G11B5/76
CPC分类号： G11B7/0062 , G11B20/08 , G11B7/00454 , G11B7/00557 , G11B20/1258
摘要： A method is described for recording an optical information carrier, in which marks representing recorded data are written at different writing speeds by radiation pulse of equal length and power, independent of the writing speed. The number of pulses per unit length of the written mark is a constant independent of the writing speed.
摘要翻译：描述了一种用于记录光学信息载体的方法，其中以与写入速度相同的长度和功率相等的辐射脉冲以不同的写入速度写入表示记录数据的标记。写入标记的每单位长度的脉冲数是独立于写入速度的常数。

10. 发明授权

US5419937A Optical record carrier 失效
标题翻译：光记录载体
公开(公告)号：US5419937A
公开(公告)日：1995-05-30
申请号：US3085
申请日：1993-01-11
申请人： James H. Coombs , Antonius H. M. Holtslag , Wilma Van Es Spiekman
发明人： James H. Coombs , Antonius H. M. Holtslag , Wilma Van Es Spiekman
IPC分类号： G11B7/24 , B32B3/00
CPC分类号： G11B7/24 , Y10S428/913 , Y10T428/31678
摘要： An optical record carrier with a substrate (1) having thereon a stack (3) of a reflection layer (4), an interference layer (5) and a phase-change recording-layer (6) in that order, the incident radiation being first incident on the reflection layer. Due to this structure of the stack a high contrast between the inscribed and uninscribed areas of the recording layer, and/or a high reflection, is obtained.
摘要翻译：一种具有基板（1）的光学记录载体，其上具有反射层（4）的叠层（3），干涉层（5）和相变记录层（6），所述入射辐射为第一个事件在反射层。由于堆叠的这种结构，获得了记录层的内接区域和未界定区域之间的高对比度和/或高反射率。

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